Just dropped: Gift Cards are here! Treat yourself or someone you love. SHOP NOW
FREE US Shipping $50+ Auto-Replenishment 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

Rewards members earn 1475 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$295.00

Or 4 interest free payments of $73.75 with


In stock | Usually dispatched within 24 hours

Image 1 - Image of a skin serum bottle labeled TNS® ADVANCED+ SERUM with a background of glass beakers, featuring the text Next Generation Skin Rejuvenation and additional claims such as Clinically proven to address sagging skin, Smooths visible coarse wrinkles and fine lines, and Results start in just 2 weeks*.
Image 2 - Image showing a side-by-side comparison of a 60-year-old females face before and after using TNS Advanced+ serum, with the Before image on the left showing visible wrinkles and the After image on the right indicating smoother skin with marked improvements at week 2, alongside text detailing baseline and improvements.
Image 3 - Image shows a cream or gel texture with text highlighting key ingredients for skincare. Visible text includes: Key Ingredients TNS-MR An advanced formula to help you get age-defying results with: + NEXT-GENERATION GROWTH FACTOR BLEND Supports healthy skin functions + INNOVATIVE PEPTIDE COMPLEX Nourishes your skin Renessence (RSC) Advanced Specifically designed to support the results of the growth factor blend and includes: + MARINE EXTRACT Supports skin’s renewal process + GREEN MICROALGAE Supports collagen and elastin levels.
Image 4 - A sleek bottle of SkinMedica TNS Advanced+ Serum is displayed next to a small amount of the serum on a light background, with the text stating that in a clinical study, after 12 weeks, patients using the serum felt they looked up to 6 years younger.
Image 5 - A pair of hands holds a cosmetic bottle with instructions on its use, including details on when and how to apply the product, and visible text that reads: How to Use, WHEN TO APPLY, In the morning and evening after cleansing and toning, HOW TO APPLY, Before applying, invert and tap the bottom of the bottle, Remove the cap and press on the center of the pump to dispense onto the back of your hand using a bunny finger application, Blend the product together before applying, Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with warm water.
Image 6 - Image of SkinMedica products arranged on a light background, including an AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA⁵ Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen, with the text Complete Your SkinMedica Method Routine above them.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.56 stars out of a maximum of 5

5 stars rating 442 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 19 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Love TNS Serum

5 stars out of a maximum of 5

I love the results from TNS Serum...brighter skin, reduces fine lines and minimizes skin discoloration!

by Marilyn Verified Purchase

Was this helpful?

Nourishment for my skin

5 stars out of a maximum of 5

This was recommended to me by my plastic surgeon to keep my skin as youthful as possible. My skin drinks it up. It gives it a glow and feels amazing. 

by Debbie Verified Purchase

Was this helpful?

Amazing!

5 stars out of a maximum of 5

I’ve been using Skin Medica products for close to 10 years. The TNS Advanced Serum was the first product I tried. I’ve used it since, and definitely recommend it!  

by Nancy Verified Purchase

Was this helpful?

Like it; not in love

3 stars out of a maximum of 5

I splurged on this purchase, expecting great results. Did make my skin feel very soft, but didn’t really see any benefit to lifting skin

by Nancy Verified Purchase

Was this helpful?

TNS serum

5 stars out of a maximum of 5

My skin fills amazing using this serum. Recommended by my dermatologist several years ago!

by Linda Verified Purchase

Was this helpful?

Great Serum

4 stars out of a maximum of 5

This is probably the fourth bottle I’ve purchased, and while I do think the dispenser could be improved it is overall a great product. Improves my fine line and definitely firms!

by Forties Verified Purchase

Was this helpful?

Love this serum

5 stars out of a maximum of 5

This serum has made my skin more uniform, brighter, more firm and with less fine lines.   I use this before tret or with Shani Darden Retinol reform and follow with Skinmedica dermal repair cream or Augustinus Bader rich.  However I feel that this serum is as important as tret or ret so a less expensive cream that is rich may be my next step.  

by stephanie Verified Purchase

Was this helpful?

Expensive for only 1 oz.

3 stars out of a maximum of 5

To be honest I have only been using this product for 3 weeks so not long enough to say IF it actually works. I am appalled by the cost of this which comes in a large container with only 1 oz. The container is opaque so it's impossible to see how much might be left. I'm already trying to figure out how to saw it open when it no longer pumps anymore so to get the very last drop as the oval top doesn't unscrew.

by Jo Verified Purchase

Was this helpful?

Amazing product

5 stars out of a maximum of 5

I have used this serum for about a year. Because it is on the pricey side, I quit using it for a while. My skin looked great and I guess I thought I didn’t need it anymore. Within a month’s time I noticed that my skin started to look less firm and overall not as radiant as it had been. I immediately renewed my subscription to the serum and within a few weeks my skin started “perking up.” So I suppose I noticed the biggest change when I stopped using it! So stick with it because it works.

by Amy Verified Purchase

Was this helpful?

Great so far

4 stars out of a maximum of 5

I have recently started using this product and so far it’s going well. The texture is smooth and it’s easy too include in my routine.my skin is looking good m, but it’s also too soon too tell beyond that. I am encouraged by my results so far. The pump has to be pressed down evenly, which is hard to do while holding the bottle. I set it down on the counter and the press with my fingers spaced apart.- It works consistently well this way.

by DV Verified Purchase

Was this helpful?

Powered by firmly · Terms · Privacy